Updated: Aug 30, 2026
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| Certification Vendor: | ACRP (Association of Clinical Research Professionals) |
|---|---|
| Exam Name: | ACRP Certified Professional (ACRP-CP) Certification Exam |
| Exam Number: | ACRP-CP |
| Related Certifications: | ACRP Certified Clinical Research Associate (CCRA) ACRP Certified Clinical Research Coordinator (CCRC) |
| Exam Format: | Computer-based testing, Multiple choice |
| Available Languages: | English |
| Real Exam Qty: | Approximately 130 |
| Exam Duration: | 180 minutes |
| Recommended Training: | ACRP Official Training & Education |
| Exam Registration: | Pearson VUE Registration Portal ACRP Certification Page |
| Sample Questions: | ACRP ACRP-CP Sample Questions |
| Exam Way: | Computer-based exam delivered via test centers and/or remote proctoring through authorized testing provider |
| Pre Condition: | Professional experience in clinical research is typically required (commonly around 2–3+ years depending on eligibility pathway); eligibility requirements vary by pathway on the official ACRP certification policy. |
| Official Syllabus URL: | https://www.acrpnet.org/ |
| Section | Objectives |
|---|---|
| Topic 1: Regulatory Compliance | - Audit and inspection readiness - Regulatory documentation and submissions |
| Topic 2: Participant Safety and Protection | - Informed consent process - Safety reporting and adverse events |
| Topic 3: Study Operations | - Study conduct and oversight - Study planning and initiation |
| Topic 4: Clinical Research Foundations | - Good Clinical Practice (GCP) principles - Ethical conduct in clinical trials |
| Topic 5: Data and Quality Management | - Quality assurance and quality control - Clinical data management principles |
Question 1
In an investigator-initiated study, who is responsible for implementing appropriate corrective and preventive actions when significant non-compliance is discovered?
A. CRC
B. PI
C. IRB/IEC
D. CRA
Question 2
When determining whether a protocol deviation (PD) is reportable to the IRB/IEC, the PI should take into consideration whether the:
A. Sponsor approved the PD.
B. PD affected participant safety.
C. Participant verbally agreed to the PD.
D. PD affected participant recruitment.
Question 3
A deferred consent can take place in which of the following situations?
A. Only when the PI approves such a consent process immediately prior to patient enrollment, regardless of the situation being classed as emergency.
B. Only when the PI approves such a consent process, regardless of the emergency situation described in the protocol.
C. In an emergency situation only, even when this process is not described in the protocol, but the sponsor approves the consent process.
D. In an emergency situation only, when this process is described in the protocol and has received permission from the ethics committee.
Question 4
A study has been closed for two years after the last approval of a marketing application of an IP. No additional applications are pending and there are no further developments planned for the IP. Which of the following statements is the BEST course of action regarding the destruction of the essential documents?
A. The site may proceed with the destruction of the essential documents.
B. The site should contact the sponsor and receive verbal notification they are no longer needed andthe essential documents may be destroyed.
C. The site should retain the essential documents longer to meet the regulatory requirements.
D. The site should contact the sponsor and receive written notification prior to destruction that the essential documents are no longer needed.
Question 5
While reviewing a new protocol, a PI realizes a specialized laboratory test is required that the local hospital does not perform. The PI locates a laboratory that performs the specialized test and retains their services.
Responsibility for ensuring the laboratory retained is qualified for this trial-related task lies with the:
A. CRC
B. PI
C. CRO
D. Sponsor
Solutions:
| Question 1 Answer: B | Question 2 Answer: B | Question 3 Answer: D | Question 4 Answer: D | Question 5 Answer: B |
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